Headline : NIH awards will support innovation in syphilis diagnostics

Read more from the original article on here at www.nih.gov.

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Initiative to simplify testing process for an accelerated public health response.

The National Institutes of Health’s National Institute of Allergy and Infectious Diseases (NIAID) has awarded grants for 10 projects to improve diagnostic tools for congenital and adult syphilis—conditions currently diagnosed with a sequence of tests, each with limited precision. The Centers for Disease Control and Prevention (CDC) estimates that adult and congenital syphilis cases increased by 80% and 183% respectively between 2018 and 2022—a crisis that prompted the U.S. Department of Health and Human Services (HHS) to establish a national taskforce to respond to the epidemic.  

“Syphilis antibiotics work, but antiquated testing makes it very difficult to ensure that people are appropriately diagnosed and fully treated,” said NIAID Director Jeanne M. Marrazzo, M.D., M.P.H. “Advanced diagnostics could streamline syphilis care and also enhance our ability to measure the efficacy of candidate syphilis vaccines and other prevention modalities.”

Syphilis is a common sexually transmitted infection caused by the bacterium Treponema pallidum. It can cause adult neurological and organ damage, as well as congenital abnormalities, stillbirths, and neonatal deaths. The CDC reports that U.S. syphilis incidence has increased since 2000, marked by a sharp rise in cases since 2019 and an escalating toll in medically underserved populations.

Read more from the original article on here at www.nih.gov.

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