Headline : The Weight Loss Drug That Can Prevent Diabetes

Read more from the original article on here at time.com.

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The weight-loss drugs that have become so popular in recent years actually began as diabetes medications, and a new study shows that they continue to provide strong protection against that chronic disease.

Eli Lilly, the makers of tirzepatide—which they sell as Mounjaro for diabetes and Zepbound for weight loss—announced recently that in its longest study yet on tirzepatide, the drug reduced the risk of people with prediabetes moving on to develop diabetes by 94% compared to those taking a placebo.

For nearly three years, the study followed more than 1,000 people who were overweight or obese and had prediabetes. By the end of the study, those on any of three doses of the drug lost up to nearly 20% of their body mass from the start of the study compared to those taking a placebo. The drug also contributed to a 94% lower chance of progressing from prediabetes to diabetes compared to placebo.

Tirzepatide targets two hormones related to appetite and weight: glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). In people with diabetes, the weekly injectable medication helps to modulate glucose levels before and after eating as well as lower weight, which in turn also regulates blood sugar levels. The study shows that people at higher risk for diabetes can use the drug to better control their blood sugar metabolism so they don’t develop the condition.

Read more from the original article on here at time.com.

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